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Symbol
Name
ID

Pde4b
phosphodiesterase 4B, cAMP specific
MGI:99557

Phenotype annotations related to nervous system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Addictive alcohol use
Disease(s) Associated with PDE4B	Addictive alcohol use
alcohol dependence

Mouse Phenotypes		nervous system phenotype	abnormal neuron differentiation	brain vacuoles	increased dendritic spine density	abnormal spinal cord morphology	abnormal CNS synaptic transmission	enhanced long-term potentiation	increased post-tetanic potentiation	decreased synaptic depression
Availability	Mouse Genotype	nervous system phenotype	abnormal neuron differentiation	brain vacuoles	increased dendritic spine density	abnormal spinal cord morphology	abnormal CNS synaptic transmission	enhanced long-term potentiation	increased post-tetanic potentiation	decreased synaptic depression
	Pde4b^enu1H/Pde4b^enu1H Tg(Thy1-EGFP)#Jrs/0
	Pde4b^enu1H/Pde4b^enu1H	*
	Pde4b^tm1Dgen/Pde4b^tm1Dgen

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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